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Calypta Health

Here’s a deck of 100 cards.

How it works

The deck is a model of how a flu season can go for you. The proportion of flu cards in the deck represents the chance that an adult your age who isn’t vaccinated gets sick with flu in a typical season: 10 flu cards out of 100 means about a 10% chance. Counts are rounded to whole cards.

AgeFlu cards, unvaccinatedFlu cards, vaccinated
18–49106
50–64159
65+85

A typical season. How many flu cards each age gets, and the hospital and death odds on the back of each card, come from CDC’s estimates of flu illness, hospitalization, and death by age, averaged over 13 seasons from 2010–11 to 2024–25. The two COVID-19 seasons are excluded. CDC’s rates are averages across everyone, including the many people who got vaccinated, so they understate the risk for someone who isn’t vaccinated. We scale CDC’s rates up to estimate the risk for unvaccinated people, using each age group’s vaccination rate and the vaccine’s typical effectiveness, following the method CDC uses to estimate the illness prevented by vaccination.

Sick with flu means symptomatic flu illness as CDC estimates it, which counts everyone who gets sick with flu, including people who never see a doctor. CDC says flu usually comes on suddenly, with fever or chills, body aches, and fatigue, and most people recover in a few days to less than two weeks. People with flu can spread it starting about a day before they feel sick.

Hospital stays and deaths. For people of each age who get sick with flu, the chance of a hospital stay (counting those who die there) and the chance of dying come from the same CDC estimates. Older adults get sick with flu less often than younger adults, but far more of them end up in the hospital or die when they do.

AgeChance of ending up in the hospital, if you get fluChance of dying, if you get flu
18–49about 1 in 180about 1 in 5,200
50–64about 1 in 94about 1 in 1,500
65+about 1 in 11about 1 in 100

The vaccine prevents about 40% of flu illness, so the wizard replaces about 40% of the flu cards with blank ones. That is the median of CDC’s season-by-season estimates of how well the vaccine prevents flu illness serious enough to see a doctor, since 2010–11. It works better some years than others: CDC’s estimates have ranged from 19% to 60%, depending on how well the vaccine matches the flu strains going around that year. The deck uses the same effectiveness at every age, which is a simplification. The standard vaccine produces a weaker immune response in older adults, which is why CDC prefers high-dose, adjuvanted, or recombinant flu vaccines at 65 and older.

If you get flu anyway. Vaccinated people who get flu may have a milder illness. In studies of adults hospitalized with flu, vaccinated patients were less likely to need intensive care or to die, but these are observational studies: people who get vaccinated also tend to be healthier in other ways, and the studies can’t fully separate the two. The flu cards that remain after the swap are drawn a little less menacing to show this.

Free for most people. Most insurance plans cover the flu vaccine with no copay at an in-network provider, and Medicare Part B pays for it in full. The $15 Walgreens offer is a store promotion for myWalgreens members (free to join), not available in every state.

Caveats. Real seasons vary widely, from mild to severe. The deck shows an average season, not a forecast for this one or a personal risk estimate. Some chronic conditions, such as asthma, heart disease, diabetes and a weakened immune system, raise the risk of serious flu at any age, as does pregnancy.

To see the same numbers play out across 10,000 adults, try the flu season simulation.

Sources

  1. CDC: Flu Disease Burden by Season and Age, 2010–11 to 2024–25 (data file)

    CDC’s estimated flu illnesses, hospitalizations, and deaths by age for each season, with population. Averaged across 13 seasons from 2010–11 to 2024–25, omitting 2020–21 (no estimate) and 2021–22, adults 65 and older had about 520 flu hospitalizations and 55 flu deaths per 100,000 people per season; adults 18 to 49 had about 46 and 1.6. The 2024–25 estimates are preliminary.

  2. Chung et al., Effects of Influenza Vaccination in the United States During the 2018–2019 Influenza Season (Clin Infect Dis 2020)

    CDC’s 2018–19 burden estimates by age. Hospitalizations per 1,000 illnesses: about 6 (18 to 49), 11 (50 to 64), and 91 (65 and older). Deaths per 1,000 illnesses: about 0.2, 0.6, and 8.3. Flu vaccination coverage that season was 35% (18 to 49), 47% (50 to 64), and 68% (65 and older).

  3. CDC: Past Seasons’ Vaccine Effectiveness Estimates

    CDC’s season-by-season effectiveness estimates since 2010–11 range from 19% (2014–15) to 60% (2010–11), with a median of 40% across 15 seasons (the two most recent still marked preliminary).

  4. CDC: Signs and Symptoms of Flu

    CDC’s cold-versus-flu table: flu onset is abrupt, fever is common and lasts 3 to 4 days, aches are often severe, and fatigue is usual; with a cold, onset is gradual, fever rare, aches slight, and fatigue only sometimes present. Most people with flu "will recover in a few days to less than two weeks."

  5. CDC: About Influenza

    Flu is "a contagious respiratory illness caused by influenza viruses that infect the nose, throat, and sometimes the lungs." "Some otherwise healthy adults may be able to infect others beginning one day before symptoms develop."

  6. CDC: Benefits of Flu Vaccination

    In seasons when the vaccine matches circulating viruses, vaccination reduced the risk of a flu-related doctor’s visit by 40% to 60%. Among adults hospitalized with flu, vaccinated patients had a 26% lower risk of ICU admission and a 31% lower risk of death from flu.

  7. Ferdinands et al., Does Influenza Vaccination Attenuate the Severity of Breakthrough Infections? (Vaccine 2021)

    Review of observational studies: among adults hospitalized with flu, vaccinated patients were less likely to be admitted to intensive care or to die.

  8. CDC: Interim Clinical Considerations for the Use of Seasonal Influenza Vaccines in the United States (2026–27)

    The July 2025 recommendations remain in effect for 2026–27. Vaccination is ideally in September or October and should continue throughout the season. No preference among vaccines under 65; high-dose, recombinant, or adjuvanted vaccine preferred for 65 and older. The nasal spray (FluMist) is approved for ages 2 through 49 and should not be used during pregnancy or with a weakened immune system.

  9. HealthCare.gov: Preventive Care Benefits for Adults

    Marketplace and many other plans must cover adult flu vaccination without a copayment or coinsurance when given by an in-network provider.

  10. Medicare.gov: Flu vaccines

    Medicare Part B covers a flu vaccine each flu season; you pay nothing if your provider accepts assignment.

  11. CDC: People at Increased Risk for Flu Complications

    Groups at higher risk of serious flu complications include adults 65 and older; pregnant women, including up to 2 weeks after the end of pregnancy; people with asthma, chronic lung disease (such as COPD), heart disease, diabetes and other endocrine disorders, kidney or liver disorders, blood disorders (such as sickle cell disease), neurologic conditions, a BMI of 40 or higher, a weakened immune system, or a history of stroke; and people who live in nursing homes and other long-term care facilities.

  12. Walgreens, Seasonal flu shots

    $15 in Walgreens Cash for myWalgreens members who get a flu shot, on an in-store purchase of $5 or more within 14 days; not offered in Arkansas, New Jersey, or New York. Checked October 1, 2026.