Measles simulated.
Interactive simulation
What happens to 1,000 unvaccinated children exposed to measles?
- High-fever illness
- 0
- Hospital care
- 0
- Death
- 0
Fever, cough, rash, and red eyes for about 10 days.
Pneumonia, brain swelling, or severe dehydration requiring hospitalization.
Fatal complications occur in roughly 1–2 per 1,000 infections.
What this shows
Risks can be hard to make sense of when they’re just numbers. This simulation makes the risk of measles tangible by exposing 1,000 unvaccinated children to it, showing how many get sick, how many need hospital care, and how many die. It then re-rolls the dice as if each child had been vaccinated. The MMR vaccine prevents the vast majority of cases, hospitalizations, and deaths.
How it works
This is a Monte Carlo simulation: for each child, we roll dice weighted by likelihood.
Catching measles. In close contact with an infected person, an unvaccinated child has about a 90% chance of infection, the secondary attack rate from the CDC’s Pink Book. High, but not certain, so a few escape even unvaccinated.
Severity. Among children who catch measles, the split into illness, hospital care, and death follows the CDC’s distribution: about one in five hospitalized, one to two per thousand fatal. Breakthrough cases follow the same split. Cases in vaccinated children may be milder; the model does not apply this severity discount.
Two doses of MMR are about 97% effective against measles disease, per the CDC. In the vaccinated re-roll, that rate governs who’s protected. Some breakthrough cases occur.
Caveats. To construct a fair comparison, the “vaccinated” scenario assumes all individuals are exposed to measles, and computes infection and complication rates accordingly. In a real-world scenario of universal vaccination, herd immunity means that very few people are ever exposed; measles simply doesn’t circulate. The simulation also omits SSPE, a rare, fatal brain disease that can strike years after initial infection.
Sources
- WHO: Measles Fact Sheet
World Health Organization fact sheet on measles. Covers disease transmission (one infected person can generate up to 18 secondary infections), complications, and mortality. WHO reports measles caused approximately 136,000 deaths globally in 2022, mostly among unvaccinated children.
- CDC: Measles Symptoms and Complications
CDC measles symptoms and complications page. Documents the ~1-in-5 hospitalization rate and the severity breakdown (ear infection, diarrhea, pneumonia, encephalitis) among US measles cases.
- CDC: Measles Vaccine Considerations
Two-dose MMR vaccine effectiveness against measles disease is about 97%.
- CDC: Epidemiology and Prevention of Vaccine-Preventable Diseases (Pink Book), 14th Edition
CDC reference for vaccine-preventable disease epidemiology. The measles chapter documents "more than 90% secondary attack rates among unvaccinated susceptible persons in close-contact settings," and also covers an R0 of 12-18 and severity figures.
- Wendorf et al.: Subacute Sclerosing Panencephalitis: The Devastating Measles Complication That Might Be More Common Than Previously Estimated (Clin Infect Dis 2017)
Age-stratified SSPE risk estimate after measles infection: 1:1,367 for children infected under age 5 and 1:609 for infants infected under 12 months, with conservative under-reporting corrections of 1:2,700 and 1:1,200 respectively. Median latency 9.5 years.
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